Basic Information

IDDRAMP18424
SequenceTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Length58
NameTLN-58 (TLN58; human cathelicidin)
Sourcethe lesion vesicle, skin, Homo sapiens
ActivityAntimicrobial, Antibacterial
PathogenActive against S. aureus, S. epidermidis, and Group A Streptococcus.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID27771329

Physicochemical Properties

Residues58
SequenceTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Molecular Weight6861.847
Grand Average of Hydropathy-0.816
Isoelectric Point10.21
Charge at pH 7.46.169
Secondary StructureHelix: 0.293, Turn: 0.190, Sheet: 0.172
Instability Index35.057
Aromaticity0.103

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Candidates based on structure

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