Basic Information

IDDRAMP04015
SequenceLLGDFFRKVKEKIGKEFKRIVQRIKDFLRNLVPRTES
Length37
NameLL-37V9 (LL-37 variants)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli DC2 (MIC=12 µM), Escherichia coli K12 (MIC=25 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22185690

Physicochemical Properties

Residues37
SequenceLLGDFFRKVKEKIGKEFKRIVQRIKDFLRNLVPRTES
Molecular Weight4505.317
Grand Average of Hydropathy-0.589
Isoelectric Point10.605
Charge at pH 7.45.547
Secondary StructureHelix: 0.378, Turn: 0.135, Sheet: 0.189
Instability Index20.27
Aromaticity0.108

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