| ID | DRAMP20955 |
|---|---|
| Sequence | LGDFFRKSKEKIGKEFKRIVQRIKDFLRNLAKRHHGYKRKFH |
| Length | 42 |
| Name | L31-P113 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | [Ref.29859288] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=25 ± 0 μg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=16.6 ± 7.2 μM);##Fungi: Candida albicans ATCC 90028 (MIC=166.6 ± 57.7 μg/mL) |
| Hemolytic Activity | [Ref.29859288] Hemolysis 12.0 ± 0.7% at 500 μg/ml against human red blood cells |
| Cytotoxicity | [Ref.29859288] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 29859288 |
Physicochemical Properties
| Residues | 42 |
|---|---|
| Sequence | LGDFFRKSKEKIGKEFKRIVQRIKDFLRNLAKRHHGYKRKFH |
| Molecular Weight | 5257.161 |
| Grand Average of Hydropathy | -1.217 |
| Isoelectric Point | 11.122 |
| Charge at pH 7.4 | 10.645 |
| Secondary Structure | Helix: 0.310, Turn: 0.119, Sheet: 0.143 |
| Instability Index | 25.412 |
| Aromaticity | 0.143 |