Basic Information

IDDRAMP02961
SequenceGLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS
Length37
NameAntibacterial peptide PMAP-37 (Myeloid antibacterial peptide 37; pigs, mammals, animals)
SourceSus scrofa (Pig)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli ML35 (MIC=2 µM), Escherichia coli ATCC 25922 (MIC=1 µM), Escherichia coli D21 (MIC=2 µM), Salmonella typhimurium ATCC 14028 (MIC=4 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=2 µM).##Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=4 µM), Bacillus megaterium local isolate (IC=4 µM), Staphylococcus aureus ATCC 25923 (MIC=32 µM), Staphylococcus aureus Cowan 1 (MIC=64 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P49932
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID7737198

Physicochemical Properties

Residues37
SequenceGLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS
Molecular Weight4364.963
Grand Average of Hydropathy-0.724
Isoelectric Point10.237
Charge at pH 7.42.554
Secondary StructureHelix: 0.324, Turn: 0.216, Sheet: 0.243
Instability Index49.286
Aromaticity0.081

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