Basic Information

IDDRAMP02925
SequenceRLKELITTGGQKIGEKIRRIGQRIKDFFKNLQPREEKS
Length38
NameCathelicidin (dogs, mammals, animals)
SourceCanis lupus familiaris (Dog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli (MIC=1.25 µM), Klebsiella pneumoniae (MIC=1.25 µM), Salmonella serotype Typhimurium (MIC=1.25 µM), Pseudomonas aeruginosa (MIC=1.25 µM), Proteus mirabilis (MIC=1.25 µM), Salmonella serotype Enteritidis (MIC=0.5 µM), Neisseria gonorrhoeae (MIC=0.06 µM).##Gram-positive bacteria: Listeria monocytogenes (MIC=0.5 µM), Staphylococcus aureus (MIC=50 µM).##Fungi: Candida albicans (MIC=12.5-50 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17462733

Physicochemical Properties

Residues38
SequenceRLKELITTGGQKIGEKIRRIGQRIKDFFKNLQPREEKS
Molecular Weight4512.225
Grand Average of Hydropathy-1.139
Isoelectric Point10.605
Charge at pH 7.45.547
Secondary StructureHelix: 0.263, Turn: 0.184, Sheet: 0.184
Instability Index29.205
Aromaticity0.053

Similar Structure Search

Candidates based on structure

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