Basic Information
| ID | DRAMP01452 |
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| Sequence | RISFKKGKGSWIKNGLIKGIKGLGKEISLDVIRTGIDIAGCKIKGEC |
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| Length | 47 |
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| Name | Esculentin-1LTa (Frogs, amphibians, animals) |
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| Source | Hylarana latouchii (Broad-folded frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=0.6 µM), Bacillus licheniformis X39 (MIC=10 µM), Staphylococcus carnosus KHS (MIC=1.3 µM), Rhodococcus rhodochrous X15 (MIC=0.3 µM);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=5 µM), Serratia rubidaea X01 (MIC=10 µM), Psychrobacter faecalis X29 (MIC=0.6 µM).##Yeast: Candida albicans ATCC2002 (MIC=80 µM). |
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| Hemolytic Activity | [Ref.22426384] LD50>480 μM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys41 and Cys47) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 22426384 |
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