Basic Information

IDDRAMP03090
SequenceGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR
Length39
NameDrosophila cecropin B (CecB; Insects, animals)
SourceDrosophila melanogaster (Fruit fly)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli D21 (MIC=1.8 µM), Enterobacter cloacae b12 (MIC=1.0 µM), Pseudomonas aeruginosa OT97 (MIC=4.2 µM);##Gram-positive bacteria: Bacillus megatherium Bm11 (MIC=3.7 µM), Bacillus subtilis Bsll (MIC=3.2 µM), Micrococcus luteus MI11 (MIC=59 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P14956, O16826, O16827, O16828, O18647, O61274, Q9V425
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID2390977, 2104802

Physicochemical Properties

Residues39
SequenceGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR
Molecular Weight4226.846
Grand Average of Hydropathy-0.3
Isoelectric Point11.568
Charge at pH 7.44.588
Secondary StructureHelix: 0.256, Turn: 0.154, Sheet: 0.282
Instability Index24.641
Aromaticity0.026

Similar Structure Search

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