Basic Information
| ID | DRAMP03162 |
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| Sequence | ATCDLLSAFGVGHAACAAHCIGHGYRGGYCNSKAVCTCRR |
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| Length | 40 |
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| Name | Phlebotomus duboscqi defensin (PduDef; defensins; Insects, animals) |
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| Source | Phlebotomus duboscqi |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Antifungal, Antiparasitic |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus (MIC=0.78-1.56 µM), Aspergillus fumigatus (MIC=12.5-25 µM).##Fungi: Fusarium culmorum (MIC=1.56-3.12 µM), Fusarium oxysporum (MIC=3.12-6.25 µM), Neurospora crassa (MIC=6.25-12.5 µM), Trichoderma viride (MIC=3.12-6.25 µM), Trichophyton mentagrophytes (MIC=25-50 µM), Candida albicans (MIC=6.25-12.5 µM), Saccharomyces cerevisiae (MIC=25-50 µM).##Parasite: Leishmania major promastigote forms (IC50=68-85 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P83404 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15557638 |
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