Basic Information
| ID | DRAMP03122 |
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| Sequence | ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN |
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| Length | 40 |
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| Name | Anopheles gambiae defensin (DEF-AAA; Insects, animals) |
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| Source | Anopheles gambiae (African malaria mosquito) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus strain 21 (IC90=6.25 µg/mL), Staphylococcus aureus strain 4 (IC90=6.25 µg/mL).##T1=100 mg/kg, T2>100 mg/kg.##T1, dose causing the first signs of toxicity on mice. T2, lethal dose. |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
Q17027, O61721, Q38L95, Q38L99, Q38LA3, Q38LA4, Q38LA6, Q38LB0, Q38LB2 |
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| PDB |
2NY8 |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 8799739, 18214975 |
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