Basic Information

IDDRAMP03121
SequenceATCDLASGFGVGSSLCAAHCLVKGYRGGYCKNKICHCRDKF
Length41
NameDef-ABB (hybrid defensins; Insects, animals)
SourceAnopheles gambiae (African malaria mosquito)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Staphylococcus aureus strain 21 (IC90>25 µg/mL), Staphylococcus aureus strain 4 (IC90>80 µg/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q17027
PDB 2NY9
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18214975

Physicochemical Properties

Residues41
SequenceATCDLASGFGVGSSLCAAHCLVKGYRGGYCKNKICHCRDKF
Molecular Weight4341.031
Grand Average of Hydropathy0.061
Isoelectric Point8.889
Charge at pH 7.43.52
Secondary StructureHelix: 0.244, Turn: 0.244, Sheet: 0.171
Instability Index19.193
Aromaticity0.098

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