Basic Information

IDDRAMP03166
SequenceIRNSLTCRFNFGICLPKRCPGRMRQIGTCF
Length30
NameP15 (deer beta-defensin; ruminant, animals)
SourceCervus elaphus (New Zealand deer)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli O111 (MIC=0.3 µg/mL);##Gram-positive bacterium: Staphylococcus aureus NCTC 4163 (MIC=1 µg/mL).##Fungi: Candida albicans 3135A (MIC=3 µg/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16011891

Physicochemical Properties

Residues30
SequenceIRNSLTCRFNFGICLPKRCPGRMRQIGTCF
Molecular Weight3489.197
Grand Average of Hydropathy-0.07
Isoelectric Point10.706
Charge at pH 7.45.457
Secondary StructureHelix: 0.267, Turn: 0.267, Sheet: 0.100
Instability Index37.143
Aromaticity0.1

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