Basic Information

IDDRAMP03181
SequenceHVDKKVADKVLLLKQLRIMRLLTRL
Length25
NameSpinigerin (Insects, animals)
SourcePseudacanthotermes spiniger (Termite)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Bacillus megaterium (MIC=0.8-1.5 µM), Micrococcus luteus (MIC=0.8-1.5 µM);##Gram-negative bacteria: Escherichia coli SBS363 (MIC=3-6 µM), E. coli D22 (MIC=3-6 µM), Klebsiella pneumoniae (MIC=50-100 µM), Salmonella typhimurium (MIC=3-6 µM), Pseudomonas aeruginosa (MIC=50-100 µM).##Fungi: Trichoderma viride (MIC=1.5-3 µM), Neurospora crassa (MIC=3-6 µM), Fusarium culmorum (MIC=1.5-3 µM), Nectria haematococca (MIC=0.4-0.8 µM), Candida albicans (MIC=3-6 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P82357
PDB 1ZRW, 1ZRV
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11053427, 16170803

Physicochemical Properties

Residues25
SequenceHVDKKVADKVLLLKQLRIMRLLTRL
Molecular Weight3000.736
Grand Average of Hydropathy0.156
Isoelectric Point11.069
Charge at pH 7.44.585
Secondary StructureHelix: 0.440, Turn: 0.000, Sheet: 0.360
Instability Index-2.644
Aromaticity0

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.