| ID | DRAMP03574 |
|---|---|
| Sequence | FKRIVQRIKDFLRNLV |
| Length | 16 |
| Name | LL-37(17-32)(C-terminal fragment of LL-37; Human, mammals, animals) |
| Source | Homo sapiens (Human) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram-, Anticancer |
| Pathogen | Gram-negative bacteria: Escherichia coli K12(MIC=20 µM).##Drug-resistant KBv cancer cells (LC50=30 µM), Drug-sensitive KB cancer cells (LC50=30 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P49913, Q71SN9 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 16637646 |
Physicochemical Properties
| Residues | 16 |
|---|---|
| Sequence | FKRIVQRIKDFLRNLV |
| Molecular Weight | 2045.476 |
| Grand Average of Hydropathy | -0.075 |
| Isoelectric Point | 11.723 |
| Charge at pH 7.4 | 3.553 |
| Secondary Structure | Helix: 0.500, Turn: 0.062, Sheet: 0.125 |
| Instability Index | 24.781 |
| Aromaticity | 0.125 |