Basic Information

IDDRAMP03613
SequenceDRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
Length43
NameBeta-defensin 114 (Beta-defensin 14, DEFB-14; Defensin, beta 114; Human, mammals, animals)
SourceHomo sapiens (Human)
ActivityAntimicrobial, Antibacterial
PathogenNo MICs found in DRAMP database
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q30KQ6, Q8NES9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16033865, 11854508

Physicochemical Properties

Residues43
SequenceDRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
Molecular Weight5221.99
Grand Average of Hydropathy-1.012
Isoelectric Point6.37
Charge at pH 7.4-0.599
Secondary StructureHelix: 0.209, Turn: 0.093, Sheet: 0.209
Instability Index67.109
Aromaticity0.07

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