Basic Information

IDDRAMP03865
SequenceRWWKIWVIRWWR
Length12
NameSub6 (Bac2A variant through six amino acids substitution)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Pseudomonas aeruginosa (MIC=31 µg/ml), Escherichia coli (MIC=4 µg/ml), Salmonella typhimurium (MIC=16 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8 µg/ml), Staphylococcus epidermidis (MIC=1 µg/ml), Enterococcus faecalis (MIC=8 µg/ml).##Yeast: Candida albicans (MIC=31 µg/ml)..
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16041366

Physicochemical Properties

Residues12
SequenceRWWKIWVIRWWR
Molecular Weight1871.24
Grand Average of Hydropathy-0.725
Isoelectric Point12
Charge at pH 7.43.555
Secondary StructureHelix: 0.667, Turn: 0.000, Sheet: 0.000
Instability Index90.483
Aromaticity0.417

Similar Structure Search

Candidates based on structure

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