| ID | DRAMP02844 |
|---|---|
| Sequence | ILAWKWAWWAWRR |
| Length | 13 |
| Name | CP10A (Indolicidin peptide derivative; mammals, animals) |
| Source | Bos taurus (Bovine) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=4 µg/ml), S. aureus SAP0017 MRSA (MIC=4 µg/ml), Staphylococcus haemolyticus Clinical isolate (MIC=2 µg/ml), S. haemolyticus Vancomycin-resistant isolate (MIC=1 µg/ml), Staphylococcus epidermidis Clinical isolate (MIC=2 µg/ml), Enterococcus faecalis ATCC 29212 (MIC=8 µg/ml), Listeria monocytogenes NCTC 7973 (MIC=1 µg/ml), Streptococcus pyogenes ATCC 19615 (MIC=1 µg/ml), Corynebacterium xerosis Lab strain (MIC=1 µg/ml).(Ref.2) |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P33046 |
| PDB | 1HR1 |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11294848 |
Physicochemical Properties
| Residues | 13 |
|---|---|
| Sequence | ILAWKWAWWAWRR |
| Molecular Weight | 1829.157 |
| Grand Average of Hydropathy | -0.285 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 2.555 |
| Secondary Structure | Helix: 0.538, Turn: 0.000, Sheet: 0.308 |
| Instability Index | 44.985 |
| Aromaticity | 0.385 |
