Basic Information
| ID | DRAMP21239 |
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| Sequence | WKRWVQRWKRWLR |
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| Length | 13 |
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| Name | FK13-a6 (Derived from FK13) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.28161291] Gram-positive bacteria : Bacillus subtilis(KCTC 3068)(MIC=8 μM), Staphylococcus epidermidis(KCTC 1917)(MIC=4 μM), Staphylococcus aureus(KCTC1621)(MIC=2 μM);##Gram-negative bacteria : Escherichia coli(KCTC 1682)(MIC=4 μM), Pseudomonas aeruginosa(KCTC 1637)(MIC=16 μM), Salmonella typhimurium(KCTC 1926)(MIC=2 μM) |
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| Hemolytic Activity | [Ref.28161291] HC50=167.5 μM against human red blood cells |
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| Cytotoxicity | [Ref.28161291] The cell viability of mouse macrophage RAW264.7 induced by FK13-a6 is 91.3%, 94.6%, 103.0%, 96.6%, 61.9% and 28.7% at peptide concentrations of 1.25, 2.5, 5, 10, 20 and 40 μM.## The cell viablity of human keratinocyte HaCaT induced by FK13 |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 28161291 |
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