Basic Information

IDDRAMP03939
SequenceGSKKPVPIIYCNRRTGKCQR
Length20
NameG20R (truncated isoform of thanatin, residue 1-20)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacteria: Aerococcus viridans (MIC=2.5-5 µM), Micrococcus luteus (MIC=2.5-5 µM), Bacillus megaterium (MIC=2.5-5 µM), Bacillus subtilis (MIC20-40 µM), Pediococcus acidilactici (MIC=20-40 µM).##Fungi: Neurospora crassa (MIC=5-10 µM), Botrytis cinerea (MIC=5-10 µM), Nectria haematococca (MIC=2.5-5 µM), Trichoderma viride (MIC=10-20 µM), Alternaria brassicicola (MIC=5-10 µM), Fusarium culmorum (MIC=10-20 µM), A. pisi (MIC=10-20 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8577744

Physicochemical Properties

Residues20
SequenceGSKKPVPIIYCNRRTGKCQR
Molecular Weight2304.74
Grand Average of Hydropathy-1.04
Isoelectric Point10.467
Charge at pH 7.45.498
Secondary StructureHelix: 0.200, Turn: 0.300, Sheet: 0.000
Instability Index41.37
Aromaticity0.05

Similar Structure Search

Candidates based on structure

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