Basic Information

IDDRAMP04031
SequenceKRWRIRVRVIRK
Length12
Nameopt5 (multiple amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Pseudomonas aeruginosa (MIC=3 µg/ml), Escherichia coli (MIC=1.6 µg/ml), Salmonella (MIC=3 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=3 µg/ml), Staphylococcus epidermidis (MIC=0.8 µg/ml).##Yeast: Candida albicans (MIC=6 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17052614

Physicochemical Properties

Residues12
SequenceKRWRIRVRVIRK
Molecular Weight1666.075
Grand Average of Hydropathy-1.15
Isoelectric Point12
Charge at pH 7.46.552
Secondary StructureHelix: 0.417, Turn: 0.000, Sheet: 0.000
Instability Index84.067
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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