| ID | DRAMP04086 |
|---|---|
| Sequence | ATCDLASKFNVNHTLCAAHCIARRYRGGYCNSKAVCVCR |
| Length | 39 |
| Name | W9F,W11V (mutant of Def-DAA defensin) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | Gram-positive bacteria: Staphylococcus aureus strain 21 (IC90=4-8 µg/mL), Staphylococcus aureus strain 4 (IC90=8-16 µg/mL). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 18214975 |
Physicochemical Properties
| Residues | 39 |
|---|---|
| Sequence | ATCDLASKFNVNHTLCAAHCIARRYRGGYCNSKAVCVCR |
| Molecular Weight | 4276.952 |
| Grand Average of Hydropathy | 0.018 |
| Isoelectric Point | 9.153 |
| Charge at pH 7.4 | 4.524 |
| Secondary Structure | Helix: 0.231, Turn: 0.179, Sheet: 0.205 |
| Instability Index | 15.867 |
| Aromaticity | 0.077 |