| ID | DRAMP04136 |
|---|---|
| Sequence | LRRLWLRANRL |
| Length | 11 |
| Name | LRR-1 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-negative bacteria: E. coli ATCC 25922 (MIC=128 µM), P. aeruginosa ATCC 27853 (MIC>128 µM), S. typhimurium C7731 (MIC>128 µM);##Gram-positive bacteria: S. epidermidis ATCC12228 (MIC>128 µM), E. faecalis ATCC 29212 (MIC>128 µM), S. aureus ATCC 29213 (MIC=128 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23430306 |
Physicochemical Properties
| Residues | 11 |
|---|---|
| Sequence | LRRLWLRANRL |
| Molecular Weight | 1466.779 |
| Grand Average of Hydropathy | -0.491 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 3.557 |
| Secondary Structure | Helix: 0.455, Turn: 0.091, Sheet: 0.455 |
| Instability Index | 128.927 |
| Aromaticity | 0.091 |