Basic Information

IDDRAMP04210
SequenceGIGKHVGKALKGLKGLLKGLGES
Length23
NameAdepantin-1 (Automatically Designed Peptide antibacterial 1; synthetic)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.19947578] Gram-negative bacteria: Escherichia coli ATCC (MIC=2-4 μM), Pseudomonas aeruginosa (MIC=16 μM).
Hemolytic Activity[Ref.19947578] HC50>800 μM against human red blood cells.
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19947578

Physicochemical Properties

Residues23
SequenceGIGKHVGKALKGLKGLLKGLGES
Molecular Weight2260.721
Grand Average of Hydropathy-0.013
Isoelectric Point10.177
Charge at pH 7.43.583
Secondary StructureHelix: 0.304, Turn: 0.348, Sheet: 0.304
Instability Index-22.252
Aromaticity0

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