| ID | DRAMP18187 |
|---|---|
| Sequence | IWLTALKFLGKNLGKHLAKQQLAKL |
| Length | 25 |
| Name | Toxin LyeTx 1 |
| Source | Lycosa erythrognatha (Spider) (Scaptocosa raptoria) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.19946788]Gram-positive bacterium: S.aureus (MIC=3.79 μM);##Gram-negative bacterium: E.coli (MIC=7.81 μM);##Yeasts: C.krusei (MIC=26.3 μM), C.neoformans (MIC=13.2 μM). |
| Hemolytic Activity | [Ref.19946788]ED50=1.3 × 10−4 M against rabbit erythrocytes |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | C0HJU9 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 19946788 |
Physicochemical Properties
| Residues | 25 |
|---|---|
| Sequence | IWLTALKFLGKNLGKHLAKQQLAKL |
| Molecular Weight | 2833.462 |
| Grand Average of Hydropathy | 0.148 |
| Isoelectric Point | 10.602 |
| Charge at pH 7.4 | 4.582 |
| Secondary Structure | Helix: 0.400, Turn: 0.120, Sheet: 0.400 |
| Instability Index | 18.112 |
| Aromaticity | 0.08 |