Basic Information

IDDRAMP18225
SequenceNKGCAICSIGAACLVDGPIPDFEIAGATGLFGLWG
Length35
NameSubtilosin A1 (Bacteriocin)
SourceBacillus subtilis
ActivityAntimicrobial, Antibacterial
Pathogen[Ref.19633086]Gram-postive bacterium:Bacillus subtilis(MIC= 250μM), Bacillus anthracis(MIC= 16μM), Bacillus cereus(MIC= 40μM), Bacillus thuringiensis(MIC= 40μM), Enterococcus faecalis(MIC= 100μM), taphylococcus carnosus(MIC= 100μM), Listeria monocytogenes(MIC= 40μM), Streptococcus pyogenes (MIC= 100μM).
Hemolytic Activity[Ref.19633086] MLC=16 μM against rabbit blood agar
CytotoxicityNo cytotoxicity information found
N-terminal ModificationNo specific N-terminal
C-terminal ModificationNo specific C-terminal
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19633086

Physicochemical Properties

Residues35
SequenceNKGCAICSIGAACLVDGPIPDFEIAGATGLFGLWG
Molecular Weight3437.96
Grand Average of Hydropathy0.84
Isoelectric Point4.05
Charge at pH 7.4-2.517
Secondary StructureHelix: 0.314, Turn: 0.314, Sheet: 0.257
Instability Index24.714
Aromaticity0.086

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