Basic Information

IDDRAMP18377
SequenceMAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLK
Length38
NameSphistin (histone-derived, Crustaceans, arthropods, invertebrates, animals)
Sourcehaemolymphs, Scylla paramamosain
ActivityAntimicrobial, Antibacterial
PathogenActive against G+ bacteria (S. aureus, C. glutamicum, B. subtilis, M. lysodeikticus, M. luteus) and G- bacteria (S. flexneri, P. stutzeri, and P. fluorescens) (MIC < 1.5 uM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25558400

Physicochemical Properties

Residues38
SequenceMAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLK
Molecular Weight3943.592
Grand Average of Hydropathy-0.616
Isoelectric Point12
Charge at pH 7.48.343
Secondary StructureHelix: 0.158, Turn: 0.263, Sheet: 0.263
Instability Index51.808
Aromaticity0.026

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