Basic Information
| ID | DRAMP18587 |
|---|
| Sequence | KWCRCVCRRGICRCRCRK |
|---|
| Length | 18 |
|---|
| Name | [Arg4,8,13][Lys18]ccTP (ccTP peptide derivative) |
|---|
| Source | Synthetic construct |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anitifungal |
|---|
| Pathogen | [Ref.10673369]Gram-positive bacteria: Staphylococcus aureus (MIC=1.7 μM in low-salt; MIC=0.7 μM in high-salt), Micrococcus luteus (MIC=0.3 μM in low-salt; MIC=0.4 μM in high-salt), Enterococcus faecalis (MIC=1.4 μM in low-salt; MIC=1.2 μM in high-salt);##Gram-negative bacteria: Escherichia coli (MIC=6.1 μM in low-salt; MIC=1.2 μM in high-salt), Pseudomonas aeruginosa (MIC=2.0 μM in low-salt; MIC=4.7 μM in high-salt), Primula vulgaris (MIC=17.0 μM in low-salt; MIC=39.8 μM in high-salt), Klebsiella oxytoca (MIC=4.1 μM in low-salt; MIC=4.1 μM in high-salt);##Fungi: Candida albicans (MIC=10.5 μM in low-salt; MIC=5.2 μM in high-salt), Candida kefyr (MIC=1.1 μM in low-salt; MIC=0.7 μM in high-salt), Candida tropicalis (MIC=2.3 μM in low-salt; MIC=1.9 μM in high-salt). |
|---|
| Hemolytic Activity | [Ref.10673369] EC25=3900 μM against human red blood cells |
|---|
| Cytotoxicity | No cytotoxicity information found |
|---|
| N-terminal Modification | No specific N-terminal |
|---|
| C-terminal Modification | No specific C-terminal |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 10673369 |
|---|
