Basic Information
| ID | DRAMP21083 |
| Sequence | KWCRCVCRRGICRCFCRG |
| Length | 18 |
| Name | ccTP 5 (Derived from TP2) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | [Ref.10673369] Gram-positive bacteria : Staphylococcus aureus(MIC=1.7 μM(low-salt);MIC=1.3 μM(high-salt)), Micrococcus luteus(MIC=0.5 μM(low-salt);MIC=0.8 μM(high-salt)), Enterococcus faecalis(MIC=0.7 μM(low-salt);MIC=0.5 μM(high-salt));##Gram-negative bacteria : Escherichia coli(MIC=5.5 μM(low-salt);MIC=1.2 μM(high-salt)), Pseudomonas aeruginosa(MIC=3.9 μM(low-salt);MIC=4.7 μM(high-salt)), Primula vulgaris(MIC=16.8 μM(low-salt);MIC=55.6 μM(high-salt)), Klebsiella oxytoca(MIC=2.4 μM(low-salt);MIC=5.4 μM(high-salt));##Fungi : Candida albicans(MIC=7.1 μM(low-salt);MIC=5.1 μM(high-salt)), Candida kefyr(MIC=4.2 μM(low-salt);MIC=0.7 μM(high-salt)), Candida tropicalis(MIC=1.9 μM(low-salt);MIC=4.8 μM(high-salt)) |
| Hemolytic Activity | [Ref.10673369] EC25=920 μM against human red blood cells |
| Cytotoxicity | [Ref.10673369] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Cyclic |
| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 10673369 |
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