ABPDB

Basic Information

ID	DRAMP18620
Sequence	KKTWWKTWWTKWSQPKKKRKV
Length	21
Name	Pep-1-K (Pep-1 peptide derivative)
Source	Synthetic construct
Activity	Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen	[Ref.16945333]Gram-positive bacteria: Bacillus subtilis (KCTC 3068) (MIC=2.0 μM), Staphylococcus aureus (KCTC 1621) (MIC=2.0 μM), Staphylococcus epidermidis (KCTC 1917) (MIC=1.0 μM);##Gram-negative bacteria: Escherichia coli (KCTC 1682) (MIC=2.0 μM), Salmonella typhimurium (KCTC 1926) (MIC=1.0 μM), Pseudomonas aeruginosa (KCTC 1637) (MIC=2.0 μM);##Antibiotic-resistant bacteria: MRSA 1 (CCARM 3001) (MIC=2.0 μM), MRSA 2 (CCARM 3089) (MIC=2.0 μM), MRSA 3 (CCARM 3543) (MIC=1.0 μM), MDRPA 1 (CCARM 2092) (MIC=8.0 μM), MDRPA 2 (CCARM 2095) (MIC=8.0 μM), MDRPA 3 (CCARM 2109) (MIC=8.0 μM).
Hemolytic Activity	[Ref.16945333]Non-hemolysis at 200 μM against human red blood cells
Cytotoxicity	Not included yet
N-terminal Modification	Not included yet
C-terminal Modification	Not included yet
Linear/Cyclic/Branched	Not included yet
Uniprot
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	16945333

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