Basic Information

IDDRAMP18700
SequenceYPELQQDLIARLL
Length13
NamePleurain-C1 (Frogs, amphibians, animals)
SourceRana pleuraden (Yunnan pond frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=50 μg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.3 μg/ml), Bacillus subtilis (MIC=3.1 μg/ml);##Yeast: Candida albicans(MIC=25 μg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot B5L1A8
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19028675

Physicochemical Properties

Residues13
SequenceYPELQQDLIARLL
Molecular Weight1571.815
Grand Average of Hydropathy0.008
Isoelectric Point4.37
Charge at pH 7.4-1.444
Secondary StructureHelix: 0.462, Turn: 0.077, Sheet: 0.462
Instability Index86.8
Aromaticity0.077

Similar Structure Search

Candidates based on structure

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