Basic Information

IDDRAMP20790
SequenceKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG
Length36
NameCecropin B (Insects, arthropods, invertebrates, animals)
SourceHyalophora cecropia (Cecropia moth)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.7019715] Gram-positive bacteria: Bacillus megaterium Bm11 (Inhibition zone=10.0 mm), Bacillus subtilis (Inhibition zone=7.2 mm);##Gram-negative bacteria: Escherichia coli K12 D31 (Inhibition zone=12.5 mm), Serratia marcescens Db1108 (Inhibition zone=7.2 mm), Pseudomonas aeruginosa OT97 (Inhibition zone=9.7 mm), Xenorhabdus nematophilus Xn21 (Inhibition zone=10.0 mm).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.7019715] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation (Leu35) PMID:3857578
Linear/Cyclic/BranchedLinear
Uniprot P01508
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID7019715

Physicochemical Properties

Residues36
SequenceKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG
Molecular Weight3892.706
Grand Average of Hydropathy-0.081
Isoelectric Point10.729
Charge at pH 7.46.542
Secondary StructureHelix: 0.306, Turn: 0.222, Sheet: 0.278
Instability Index34.717
Aromaticity0.056

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