Basic Information

IDDRAMP20798
SequenceQGVRNSQSCRRNKGICVPIRCPGSMRQIGTCLGAQVKCCRRK
Length42
NameLingual antimicrobial peptide (LAP, beta defensin, cattle, ruminant, animals)
SourceBos taurus (Bovine)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.7886453] Gram-positive bacterium: Staphylococcus aureus 29213 (MIC=63-125 μg/ml);##Gram-negative bacteria: Escherichia coli D31 (MIC=16-32 μg/ml), Pseudomonas aeruginosa 27853 (MIC=63-125 μg/ml);##Fungi: Candida albicans 14053 (MIC=32-63 μg/ml), Candida tropicalis 13803 (MIC=16-32 μg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.7886453] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot Q28880
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID7886453

Physicochemical Properties

Residues42
SequenceQGVRNSQSCRRNKGICVPIRCPGSMRQIGTCLGAQVKCCRRK
Molecular Weight4649.532
Grand Average of Hydropathy-0.569
Isoelectric Point10.846
Charge at pH 7.49.403
Secondary StructureHelix: 0.167, Turn: 0.286, Sheet: 0.071
Instability Index75.548
Aromaticity0

Similar Structure Search

Candidates based on structure

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