ABPDB

Basic Information

ID	DRAMP20960
Sequence	ILKKLLKKVKSI
Length	12
Name	Hp1404-T1d
Source	Synthetic construct
Activity	Antimicrobial, Antibacterial, Anti-Gram-
Pathogen	[Ref.29379033] Gram-negative bacteria: Pseudomonas aeruginosa ATCC 27853 (MIC=1.56 μM), Pseudomonas aeruginosa 138 (MIC=12.5 μM), Pseudomonas aeruginosa 431 (MIC=3.13 μM), Pseudomonas aeruginosa 434 (MIC=3.13 μM), Pseudomonas aeruginosa 557 (MIC=3.13 μM), Pseudomonas aeruginosa 559 (MIC=12.5 μM), Pseudomonas aeruginosa 778 (MIC=3.13 μM), Pseudomonas aeruginosa 1034 (MIC=3.13 μM), Pseudomonas aeruginosa 1162 (MIC=1.56 μM), Pseudomonas aeruginosa 3290 (MIC=6.25 μM), Pseudomonas aeruginosa 3399 (MIC=1.56 μM), Pseudomonas aeruginosa 3543 (MIC=25 μM), Pseudomonas aeruginosa 3592 (MIC=3.13 μM), Pseudomonas aeruginosa 3904 (MIC=6.25 μM), Pseudomonas aeruginosa 4007 (MIC=6.25 μM), Pseudomonas aeruginosa 4319 (MIC=3.13 μM), Pseudomonas aeruginosa 4891 (MIC=3.13 μM), Pseudomonas aeruginosa 5018 (MIC=1.56 μM), Pseudomonas aeruginosa 671973 (MIC=1.56 μM)
Hemolytic Activity	[Ref.29379033] Hp1404-T1d does not induce substantial hemolysis, even at the high tested concentration (200 μM) against mouse red blood cells
Cytotoxicity	[Ref.29379033] The cell survial against HaCaT cells is 58%, 48%, 52% and 34% at peptide concentrations of 25, 50, 100 and 200 μM
N-terminal Modification	Free
C-terminal Modification	Amidation
Linear/Cyclic/Branched	Linear
Uniprot
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	29379033

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