| ID | DRAMP20886 |
|---|---|
| Sequence | ILKKLLEGVKSI |
| Length | 12 |
| Name | Hp1404-T1b |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
| Pathogen | [Ref.29379033] Gram-negative bacteria: Pseudomonas aeruginosa 434 (MIC=25 μM), Pseudomonas aeruginosa 3592 (MIC=25 μM) |
| Hemolytic Activity | [Ref.29379033] Hp1404-T1b does not induce substantial hemolysis, even at the high tested concentration (200μμM) against mouse red blood cells |
| Cytotoxicity | [Ref.29379033] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 29379033 |
Physicochemical Properties
| Residues | 12 |
|---|---|
| Sequence | ILKKLLEGVKSI |
| Molecular Weight | 1340.694 |
| Grand Average of Hydropathy | 0.683 |
| Isoelectric Point | 9.703 |
| Charge at pH 7.4 | 1.551 |
| Secondary Structure | Helix: 0.500, Turn: 0.167, Sheet: 0.333 |
| Instability Index | 8.667 |
| Aromaticity | 0 |