Basic Information

IDDRAMP20885
SequenceILKKLWEGVKSI
Length12
NameHp1404-T1a
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.29379033] Gram-negative bacteria: Pseudomonas aeruginosa 431 (MIC=25 μM), Pseudomonas aeruginosa 434 (MIC=25 μM), Pseudomonas aeruginosa 3399 (MIC=25 μM), Pseudomonas aeruginosa 3592 (MIC=12.5 μM), Pseudomonas aeruginosa 3904 (MIC=25 μM), Pseudomonas aeruginosa 4891 (MIC=25 μM), Pseudomonas aeruginosa 671973 (MIC=25 μM)
Hemolytic Activity[Ref.29379033] Hp1404-T1a does not induce substantial hemolysis, even at the high tested concentration (200μμM) against mouse red blood cells
Cytotoxicity[Ref.29379033] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29379033

Physicochemical Properties

Residues12
SequenceILKKLWEGVKSI
Molecular Weight1413.746
Grand Average of Hydropathy0.292
Isoelectric Point9.703
Charge at pH 7.41.551
Secondary StructureHelix: 0.500, Turn: 0.167, Sheet: 0.250
Instability Index28.4
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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