Basic Information

IDDRAMP20995
SequenceKLLKFIKKLL
Length10
Nameanoplin analog 5
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.27862650]Gram-positive bacteria : Mycobacteria smegmatis mc2 155 (MIC=15 μg/ml), Bacillus subtilis DELTA (MIC=40 μg/ml);##Gram-negative bacteria : Escherichia coli DH5a (MIC=400 μg/ml), Zymomonas mobilis 10988 (MIC=10 μg/ml);##Fungi : Candida parapsilosis (MIC=30 μg/ml)
Hemolytic Activity[Ref.27862650]0% hemolysis at 100 μg/ml , 4% hemolysis at 200 μg/ml , 11% hemolysis at 300 μg/ml , 13% hemolysis at 400 μg/ml , 15% hemolysis at 500 μg/ml against human red blood cells
Cytotoxicity[Ref.27862650] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID27862650

Physicochemical Properties

Residues10
SequenceKLLKFIKKLL
Molecular Weight1243.666
Grand Average of Hydropathy0.69
Isoelectric Point10.478
Charge at pH 7.43.547
Secondary StructureHelix: 0.600, Turn: 0.000, Sheet: 0.400
Instability Index-24.96
Aromaticity0.1

Similar Structure Search

Candidates based on structure

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