Basic Information

IDDRAMP29110
SequenceLNLAALLAVAKKIL
Length14
NameMastoparan-C [K4A]
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-
Pathogen[Ref.33285267]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=4 µM); Bacillus subtilis ATCC 23857(MIC=16 µM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=8 µM); Pseudomonas aeruginosa ATCC 9027(MIC=32 µM); Klebsiella pneumoniae ATCC 700603(MIC=32 µM).
Hemolytic Activity[Ref.33285267]10% hemolysis against mouse erythrocytes at 128 µM,52% hemolysis against mouse erythrocytes at 256 µM.
Cytotoxicity[Ref.33285267]No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P01516
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID33285267

Physicochemical Properties

Residues14
SequenceLNLAALLAVAKKIL
Molecular Weight1450.851
Grand Average of Hydropathy1.686
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.500, Turn: 0.071, Sheet: 0.643
Instability Index16.979
Aromaticity0

Similar Structure Search

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