| ID | DRAMP29114 |
|---|---|
| Sequence | LNLKALLAVAAKIL |
| Length | 14 |
| Name | Mastoparan-C [K11A] |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.33285267]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=4 µM); Bacillus subtilis ATCC 23857(MIC=16 µM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=8 µM); Pseudomonas aeruginosa ATCC 9027(MIC=32 µM); Klebsiella pneumoniae ATCC 700603(MIC=32 µM). |
| Hemolytic Activity | [Ref.33285267]18% hemolysis against mouse erythrocytes at 256 µM. |
| Cytotoxicity | [Ref.33285267]No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | P01516 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 33285267 |
Physicochemical Properties
| Residues | 14 |
|---|---|
| Sequence | LNLKALLAVAAKIL |
| Molecular Weight | 1450.851 |
| Grand Average of Hydropathy | 1.686 |
| Isoelectric Point | 10.003 |
| Charge at pH 7.4 | 1.552 |
| Secondary Structure | Helix: 0.500, Turn: 0.071, Sheet: 0.643 |
| Instability Index | 10.914 |
| Aromaticity | 0 |
