Basic Information

IDDRAMP21029
SequenceATYRTGRATRESLSGVEISGRLYRLR
Length26
NameD5R (Derived from HD5)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26206286]Gram-positive bacteria : Staphylococcus aureus (NCTC 8530)(MIC=100 μM), Bacillus subtilis (NCIM 2162)(MIC=20 μM);##Gram-negative bacteria : Escherichia coli (MG 1655)(MIC=50 μM), Pseudomonas aeruginosa (NCTC 6750)(MIC=100 μM);##Fungi : Candida albicans (ATCC 18804)(MIC=20 μM), Saccharomyces cerevisiae (BY4741)(MIC=100 μM)
Hemolytic Activity[Ref.26206286] 0% hemolysis at 100μM against human red blood cells
Cytotoxicity[Ref.26206286] No cytotoxic information found.
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26206286

Physicochemical Properties

Residues26
SequenceATYRTGRATRESLSGVEISGRLYRLR
Molecular Weight2969.319
Grand Average of Hydropathy-0.715
Isoelectric Point11.345
Charge at pH 7.43.605
Secondary StructureHelix: 0.269, Turn: 0.231, Sheet: 0.269
Instability Index15.565
Aromaticity0.077

Similar Structure Search

Candidates based on structure

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