Basic Information
| ID | DRAMP21091 |
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| Sequence | RFRRLRIKTRIRLKKI |
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| Length | 16 |
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| Name | I4 (Derived from PRW4) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.25735802] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=64 μM), Staphylococcus epidermidis 12228(MIC=16 μM), Enterococcus faecalis 29212(MIC=16 μM);##Gram-negative bacteria : Escherichia coli 25922(MIC=8 μM), Escherichia coli 1005(MIC=16 μM), Salmonella typhimurium 7731(MIC=16 μM) |
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| Hemolytic Activity | [Ref.25735802] MHC5>256 μM against human red blood cells |
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| Cytotoxicity | [Ref.25735802] The peptide exhibited no cytoxicity against HaCaT cells in the range of 0/25-256 μM. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 25735802 |
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