ABPDB

Basic Information

ID	DRAMP21124
Sequence	RFRRLRKKTRKRLKKI
Length	16
Name	RI16 (Derived from PMAP-36)
Source	Synthetic construct
Activity	Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen	[Ref.25494332] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=128 μM), Staphylococcus epidermidis 12228(MIC=32 μM), ;##Gram-negative bacteria : Escherichia coli 25922(MIC=128 μM), Salmonella typhimurium 7731(MIC=128 μM), Pseudomonas aeruginosa 27853(MIC=256 μM), Pseudomonas aeruginosa 10419(MIC=256 μM), Pseudomonas aeruginosa 21625(MIC=256 μM), Pseudomonas aeruginosa 21630(MIC=256 μM), Pseudomonas aeruginosa LC(MIC=32 μM), Pseudomonas aeruginosa LCCI(MIC=256 μM), Pseudomonas aeruginosa LCGE(MIC=256 μM), Pseudomonas aeruginosa LCCE(MIC=256 μM)
Hemolytic Activity	[Ref.25494332] HC50>256 μM against human red blood cells
Cytotoxicity	[Ref.25494332] The LD50 of J774.1 macrophage cells is larger than 256 μM
N-terminal Modification	Free
C-terminal Modification	Amidation
Linear/Cyclic/Branched	Linear
Uniprot
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	25494332

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