Basic Information
| ID | DRAMP21151 |
|---|
| Sequence | LRIVKLILKWLR |
|---|
| Length | 12 |
|---|
| Name | KR-12-a6 (Derived from KR-12) |
|---|
| Source | Synthetic construct |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.24105706] Gram-positive bacteria : Bacillus subtilis (KCTC 3068)(MIC=8 μM), Staphylococcus epidermidis (KCTC 1917)(MIC=2 μM), Staphylococcus aureus (KCTC 1621)(MIC=4 μM);##Gram-negative bacteria : Escherichia coli (KCTC 1682)(MIC=16 μM), Pseudomonas aeruginosa (KCTC 1637)(MIC=16 μM), Salmonella typhimurium (KCTC 1926)(MIC=4 μM) |
|---|
| Hemolytic Activity | [Ref.24105706] HC50=22 μM against human red blood cells |
|---|
| Cytotoxicity | [Ref.24105706] The cell viability of RAW264.7 macrophage cells is 100%, 99.1%, 100%, 98.8%, 99.9%, 85.3%, 5.9% and 0% at peptide concentrations of 0.78, 1.56, 3.12, 6.25, 12.5, 25, 50 and 100 μM. |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Amidation |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 24105706 |
|---|
