| ID | dbAMP16842 |
|---|---|
| Sequence | KRIVKLLLKWLR |
| Length | 12 |
| Name | Synthetic construct&&LL-37 KR-12-a5 [I7l]&&KR-12-a5 (7-(D)L) (Derived from LL-37) |
| Source | Synthetic construct |
| Activity | Antibacterial |
| Pathogen | [Ref.28525841] GrµM-positive bacteria : Bacillus subtilis(KCTC 3068)µMIC=2 µM), Staphylococcus epideµMidis(KCTC 1917)µMIC=4 µM), Staphylococcus aureus(KCTC1621)µMIC=2 µM);&&GrµM-negative bacteria : Escherichia coli(KCTC 1682)µMIC=4 µM), PseudµMonas aerugi |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 28525841, 28525841 |
Physicochemical Properties
| Residues | 12 |
|---|---|
| Sequence | KRIVKLLLKWLR |
| Molecular Weight | 1566.033 |
| Grand Average of Hydropathy | 0.192 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 4.55 |
| Secondary Structure | Helix: 0.583, Turn: 0.000, Sheet: 0.333 |
| Instability Index | 39.042 |
| Aromaticity | 0.083 |