| ID | DRAMP21199 |
|---|---|
| Sequence | GANAAKKFANLIKKIFNYIW |
| Length | 20 |
| Name | GW-M3 (De novo synthesis) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.18586467] Gram-positive bacteria : Staphylococcus aureus (BCRC 10780)(MIC=8 μg/ml), Staphylococcus xylosus (BCRC 12930)(MIC=16 μg/ml), Staphylococcus aureus (BCRC 10781)(MIC=16 μg/ml), Listeria monocytogenes (BCRC 14845)(MIC=32 μg/ml), Streptococcus bovis (BCRC 14729)(MIC=128 μg/ml), Streptococcus iniae (laboratory strain)(MIC=128 μg/ml), Lactococcus garvieae (laboratory strain)(MIC=128 μg/ml);##Gram-negative bacteria : Klebsiella oxytoca (BCRC 13985)(MIC=32 μg/ml), Pseudomonas aeruginosa (BCRC 10944)(MIC=32 μg/ml), Escherichia coli (BCRC 10675)(MIC=16 μg/ml), Enterobacter aerogenes (BCRC 10370)(MIC=16 μg/ml), Enterobacter cloacae (BCRC 10401)(MIC=16 μg/ml), Yersinia enterocolitica (BCRC 13999)(MIC=128 μg/ml) |
| Hemolytic Activity | [Ref.18586467] MHC=8 μM against human red blood cells |
| Cytotoxicity | [Ref.18586467] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 18586467 |
Physicochemical Properties
| Residues | 20 |
|---|---|
| Sequence | GANAAKKFANLIKKIFNYIW |
| Molecular Weight | 2310.736 |
| Grand Average of Hydropathy | 0.07 |
| Isoelectric Point | 10.177 |
| Charge at pH 7.4 | 3.545 |
| Secondary Structure | Helix: 0.400, Turn: 0.200, Sheet: 0.250 |
| Instability Index | -3.235 |
| Aromaticity | 0.2 |
