| ID | DRAMP21205 |
|---|---|
| Sequence | HLNKRVQRELIRWLDWLK |
| Length | 18 |
| Name | AmyI-1-18 (G12R) (Derived from AmyI-1-18) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram-, Antifungal |
| Pathogen | [Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=4.6±1.1 μM). ##[Ref.26850838] Fungi: Candida albicans(IC50=61±8 μM) |
| Hemolytic Activity | [Ref.27478151] 2% hemolysis at 50 μM against human red blood cells |
| Cytotoxicity | [Ref.27478151##26850840] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 27478151, 26850840 |
Physicochemical Properties
| Residues | 18 |
|---|---|
| Sequence | HLNKRVQRELIRWLDWLK |
| Molecular Weight | 2403.828 |
| Grand Average of Hydropathy | -0.911 |
| Isoelectric Point | 10.904 |
| Charge at pH 7.4 | 2.591 |
| Secondary Structure | Helix: 0.444, Turn: 0.056, Sheet: 0.278 |
| Instability Index | 81.528 |
| Aromaticity | 0.111 |