| ID | DRAMP21206 |
|---|---|
| Sequence | HLNKRVQRELIGWLRWLK |
| Length | 18 |
| Name | AmyI-1-18 (D15R) (Derived from AmyI-1-18) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram-, Antifungal |
| Pathogen | [Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=11±1 μM). ##[Ref.26850838] Fungi: Candida albicans(IC50=31±4 μM) |
| Hemolytic Activity | [Ref.27478151] 2% hemolysis at 50 μM against human red blood cells |
| Cytotoxicity | [Ref.27478151##26850841] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 27478151, 26850841 |
Physicochemical Properties
| Residues | 18 |
|---|---|
| Sequence | HLNKRVQRELIGWLRWLK |
| Molecular Weight | 2345.792 |
| Grand Average of Hydropathy | -0.739 |
| Isoelectric Point | 11.723 |
| Charge at pH 7.4 | 3.59 |
| Secondary Structure | Helix: 0.444, Turn: 0.111, Sheet: 0.278 |
| Instability Index | 99.083 |
| Aromaticity | 0.111 |