Basic Information
| ID | DRAMP21257 |
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| Sequence | WLSKTAKKLWLSKTAKKLWLSKTAKKL |
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| Length | 27 |
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| Name | WL3 (Derived from CP-1) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.29266746] Gram-positive bacteria : Staphylococcus aureus ATCC 29213(MIC=32 μM), Staphylococcus aureus ATCC 43300(MIC=32 μM), Staphylococcus epidermidis ATCC 12228(MIC=32 μM), Bacillus subtilis CMCC 63501(MIC=8 μM);##Gram-negative bacteria : Escherichia coli ATCC25922(MIC=2 μM), Escherichia coli UB1005(MIC=2 μM), Pseudomonas aeruginosa ATCC 27853(MIC=2 μM), Salmonella typhimurium ATCC 7731(MIC=8 μM), Salmonella pullorum C79-13(MIC=2 μM) |
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| Hemolytic Activity | [Ref.29266746] MHC5>128 μM against human red blood cells |
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| Cytotoxicity | [Ref.29266746] The cell viability of IPEC-J2 cells induced by WL3 is 97.0%, 100.4%, 91.4%, 91.5%, 87.2%, 86.7% and 78.7% at peptide concentrations of 2, 4, 8, 16, 32, 64 and 128 μM. The cell viability of IPEC-J2 cells induced by the control Melittin is |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 29266746 |
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