Basic Information
| ID | DRAMP21256 |
|---|
| Sequence | WLSKTAKKLWLSKTAKKL |
|---|
| Length | 18 |
|---|
| Name | WL2 (Derived from CP-1) |
|---|
| Source | Synthetic construct |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.29266746] Gram-positive bacteria : Staphylococcus aureus ATCC 29213(MIC=128 μM), Staphylococcus aureus ATCC 43300(MIC=128 μM), Staphylococcus epidermidis ATCC 12228(MIC=128 μM), Bacillus subtilis CMCC 63501(MIC=64 μM);##Gram-negative bacteria : Escherichia coli ATCC25922(MIC=8 μM), Escherichia coli UB1005(MIC=8 μM), Pseudomonas aeruginosa ATCC 27853(MIC=16 μM), Salmonella typhimurium ATCC 7731(MIC=32 μM), Salmonella pullorum C79-13(MIC=16 μM) |
|---|
| Hemolytic Activity | [Ref.29266746] MHC5>128 μM against human red blood cells |
|---|
| Cytotoxicity | [Ref.29266746] The cell viability of IPEC-J2 cells induced by WL2 is 99.0%, 95.0%, 89%, 89.8%, 85.2%, 86.8% and 75.1% at peptide concentrations of 2, 4, 8, 16, 32, 64 and 128 μM. The cell viability of IPEC-J2 cells induced by the control Melittin is 77. |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Amidation |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 29266746 |
|---|
