Basic Information

IDDRAMP29029
SequenceKLLKKGGKLLKKGGKLLKKGG
Length21
NameStripe-based foldamer peptide 1
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.33369262] Gram-positive bacteria: Staphylococcus aureus NBRC13276 (MIC > 50 μM) ;##Gram-negative bacteria: Escherichia coli DH5α (MIC = 12.5 μM), Pseudomonas aeruginosa NBRC13275 (MIC > 50 μM), multidrug-resistant Pseudomonas aeruginosa ATCCBAA-2111 (MDRP) (MIC > 50 μM)
Hemolytic Activity[Ref.33369262] Peptide 1 showed no hemolytic activity up to a concentration of 100 μM.
CytotoxicityNo cytotoxicity information found in the reference
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID33369262

Physicochemical Properties

Residues21
SequenceKLLKKGGKLLKKGGKLLKKGG
Molecular Weight2192.819
Grand Average of Hydropathy-0.7
Isoelectric Point10.903
Charge at pH 7.48.535
Secondary StructureHelix: 0.286, Turn: 0.286, Sheet: 0.286
Instability Index-17.319
Aromaticity0

Similar Structure Search

Candidates based on structure

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