Basic Information
| ID | DRAMP21260 |
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| Sequence | AAKAAAKAAAKAA |
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| Length | 13 |
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| Name | KL0A10 (De novo synthesis) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.26385363] Gram-positive bacteria : Staphylococcus aureus ATCC 29213(MIC>128 μM), Staphylococcus epidermidis ATCC 12228(MIC>128 μM), Streptococcus faecalis ATCC 29212(MIC>128 μM), Bacillus subtilis CMCC 63501(MIC>128 μM);##Gram-negative bacteria : Escherichia coli ATCC25922(MIC>128 μM), Escherichia coli K88(MIC>128 μM), Escherichia coli CVCC 1515(MIC>128 μM), Escherichia coli UB1005(MIC>128 μM), Bacterium pyocyaneum ATCC 27853(MIC>128 μM), Salmonella typhimurium ATCC 14028(MIC>128 μM), Salmonella pullorum C79–13(MIC>128 μM) |
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| Hemolytic Activity | [Ref.26385363] MHC5>256 μM against human red blood cells |
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| Cytotoxicity | [Ref.26385363] The cell viability of HEK293 cells induced by KL0A10 is 103.9%, 110%, 110.6%, 107.8%, 110.3%, 110.1%, 107.2% and 106.1% at peptide concentrations of 1, 2, 4, 8, 16, 32, 64 and 128 μM. The cell viability of HEK293 cells induced by control M |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 26385363 |
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