| ID | DRAMP29068 |
|---|---|
| Sequence | kFwSLLkKAlrLwKkVL |
| Length | 17 |
| Name | CPF-2-1 (Variant of CPF-C1) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | [Ref.32590058] Gram-positive: S. aureus ATCC 25923 (MIC = 16 μg/mL, MIC = 16 μg/mL in 10% serum, MIC = 32 μg/mL in 150 mM) |
| Hemolytic Activity | [Ref.32590058]It showed almost no hemolytic activity, even at concentrations up to 128 μg/ml. |
| Cytotoxicity | Not found |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 32590058 |
Physicochemical Properties
| Residues | 17 |
|---|---|
| Sequence | kFwSLLkKAlrLwKkVL |
| Molecular Weight | 2157.73 |
| Grand Average of Hydropathy | 0.071 |
| Isoelectric Point | 11.388 |
| Charge at pH 7.4 | 5.545 |
| Secondary Structure | Helix: 0.529, Turn: 0.059, Sheet: 0.353 |
| Instability Index | 24.682 |
| Aromaticity | 0.176 |